Tramadol

Ultram, ConZip

Analgesic • Opioid / SNRI hybrid

SerotoninergicCNS Depressant

Half-life

6-7 hours

Protein Binding

20%

Metabolized By

CYP2D6, CYP3A4

External

Weak mu-opioid agonist + serotonin/norepinephrine reuptake inhibitor

Drug Class

Analgesic

Subclass

Opioid / SNRI hybrid

UltramConZip

Half-life

6-7 hours

Time for plasma concentration to decrease by 50%

Protein Binding

20%

Fraction bound to plasma proteins

Therapeutic Index

Wide

Margin between therapeutic and toxic doses