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  3. /Tramadol

Tramadol

Ultram, ConZip, Qdolo, Seglentis, Ultracet

Analgesic • Opioid / SNRI hybrid

Premium
SerotoninergicCNS Depressant

Half-life

6-7 hours

Protein Binding

Metabolized By

CYP2D6, CYP3A4

External

Drugs.com

Mechanism of Action

Weak mu-opioid agonist + serotonin/norepinephrine reuptake inhibitor

Classification

Drug Class

Analgesic

Subclass

Opioid / SNRI hybrid

Brand Names

UltramConZipQdoloSeglentisUltracet

Key Properties

Half-life

6-7 hours

Time for plasma concentration to decrease by 50%

Protein Binding

—

Fraction bound to plasma proteins

Therapeutic Index

Wide

Margin between therapeutic and toxic doses

Not a substitute for clinical judgement
Tramadol Drug Profile | PharmaGraphX