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Prozac, Sarafem
Antidepressant • SSRI
Half-life
1-3 days (norfluoxetine 4-16 days)
Protein Binding
94.5%
Metabolized By
CYP2D6, CYP2C9
External
Drugs.comSelectively inhibits serotonin reuptake; active metabolite norfluoxetine
Drug Class
Antidepressant
Subclass
SSRI
Half-life
1-3 days (norfluoxetine 4-16 days)
Time for plasma concentration to decrease by 50%
Protein Binding
94.5%
Fraction bound to plasma proteins
Therapeutic Index
Wide
Margin between therapeutic and toxic doses