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Nolvadex, Soltamox
Antineoplastic • Selective estrogen receptor modulator (SERM)
PremiumHalf-life
5-7 days
Protein Binding
>99%
Metabolized By
CYP2D6, CYP3A4, CYP2C9, CYP2C19, CYP2B6
External
Drugs.comCompetitively inhibits estrogen binding to ER-positive breast cancer cells
From the drug index — may include conditions studied rather than approved indications
1 curated · 1 major or contraindicated · select a row for management
| Interacting drug | Severity | Effect |
|---|---|---|
| fluoxetine | major | Reduced tamoxifen efficacy; increased breast cancer recurrence risk |
No significant interaction
Not recorded for Tamoxifen. Absence here means this database does not hold a category — not that the drug is safe in pregnancy or breastfeeding.
Assembled from: drug index, curated drug database, curated interaction pairs.
