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Wellbutrin, Wellbutrin SR, Wellbutrin XL, Zyban
Antidepressant • NDRI (Norepinephrine-dopamine reuptake inhibitor)
Inhibits reuptake of norepinephrine and dopamine; no serotonergic activity
Drug Class
Antidepressant
Subclass
NDRI (Norepinephrine-dopamine reuptake inhibitor)
Half-life
21 hours
Time for plasma concentration to decrease by 50%
Protein Binding
84%
Fraction bound to plasma proteins
Therapeutic Index
Wide
Margin between therapeutic and toxic doses