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Eliquis
Anticoagulant • Direct factor Xa inhibitor
PremiumHalf-life
12 hours
Protein Binding
87%
Metabolized By
CYP3A4, CYP1A2, CYP2A6, CYP2B6, CYP2C8, CYP2C9, CYP2D6, CYP2C19
External
Drugs.comDirectly inhibits factor Xa, reducing thrombin generation
From the drug index — may include conditions studied rather than approved indications
3 curated · 3 major or contraindicated · select a row for management
| Interacting drug | Severity | Effect |
|---|---|---|
| ketoconazole | contraindicated | Major bleeding risk |
| cocaine | major | Hypertensive crisis, arrhythmias, and impaired hemostasis increase stroke and hemorrhage risk |
| rifampicin | major | Substantially reduced anticoagulant effect; increased thromboembolic risk. |
Alcohol may increase bleeding risk
Not recorded for Apixaban. Absence here means this database does not hold a category — not that the drug is safe in pregnancy or breastfeeding.
Assembled from: drug index, curated drug database, curated interaction pairs.
