Apixaban

Eliquis

Anticoagulant • Direct factor Xa inhibitor

Bleeding

Half-life

12 hours

Protein Binding

87%

Metabolized By

CYP3A4

External

Directly inhibits factor Xa, reducing thrombin generation

Drug Class

Anticoagulant

Subclass

Direct factor Xa inhibitor

Eliquis

Half-life

12 hours

Time for plasma concentration to decrease by 50%

Protein Binding

87%

Fraction bound to plasma proteins

Therapeutic Index

Wide

Margin between therapeutic and toxic doses