Quetiapine Drug Profile

Boxed warning

Boxed warning

2 boxed warnings

QT prolongation

Avoid combining with other QT-prolonging agents; check electrolytes

Anticholinergic

Adds to anticholinergic burden, particularly in older patients

CNS depressant

Additive sedation with other CNS depressants and alcohol

Antagonist at dopamine D2, serotonin 5-HT2A, histamine H1, and adrenergic receptors

From the drug index — may include conditions studied rather than approved indications

1 curated · 1 major or contraindicated · select a row for management

Interacting drug	Severity	Effect
rifampicin	major	Loss of antipsychotic efficacy; risk of psychotic relapse.

Alcohol · major

Severe CNS and respiratory depression. Avoid.

Not recorded for Quetiapine. Absence here means this database does not hold a category — not that the drug is safe in pregnancy or breastfeeding.

Assembled from: drug index, curated drug database, curated interaction pairs.