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Dilantin
Antiepileptic • Hydantoin
Half-life
7-42 hours (dose-dependent)
Protein Binding
90%
Metabolized By
CYP2C9, CYP2C19
External
Drugs.comBlocks voltage-gated sodium channels; zero-order kinetics at therapeutic levels
Drug Class
Antiepileptic
Subclass
Hydantoin
Half-life
7-42 hours (dose-dependent)
Time for plasma concentration to decrease by 50%
Protein Binding
90%
Fraction bound to plasma proteins
Therapeutic Index
Narrow
Margin between therapeutic and toxic doses