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  3. /Mycophenolate Mofetil

Mycophenolate Mofetil

CellCept, Myfortic, Myhibbin

Immunosuppressant • IMPDH inhibitor

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Half-life

17.9 hours (MPA)

Protein Binding

Metabolized By

UGT

External

Drugs.com

Mechanism of Action

Inhibits inosine monophosphate dehydrogenase, blocking purine synthesis in lymphocytes

Indications(5)

Granulomatosis With PolyangiitisAnti-neutrophil Cytoplasmic Antibody-associated VasculitisAMLMDSAcute Leukemia

Classification

Drug Class

Immunosuppressant

Subclass

IMPDH inhibitor

Brand Names

CellCeptMyforticMyhibbin

Key Properties

Half-life

17.9 hours (MPA)

Time for plasma concentration to decrease by 50%

Protein Binding

—

Fraction bound to plasma proteins

Therapeutic Index

Wide

Margin between therapeutic and toxic doses

Not a substitute for clinical judgement
Mycophenolate Mofetil Drug Profile | PharmaGraphX