Linezolid

Zyvox

Antibiotic • Oxazolidinone

Serotoninergic

Half-life

4.5-5.5 hours

Protein Binding

31%

Metabolized By

N/A

External

Binds to 23S rRNA of 50S ribosomal subunit, inhibiting initiation of translation

Drug Class

Antibiotic

Subclass

Oxazolidinone

Zyvox

Half-life

4.5-5.5 hours

Time for plasma concentration to decrease by 50%

Protein Binding

31%

Fraction bound to plasma proteins

Therapeutic Index

Wide

Margin between therapeutic and toxic doses