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Tegretol, Tegretol XR, Carbatrol
Antiepileptic • Sodium channel blocker
Half-life
25-65 hours initially, then 12-17 hours (auto-induction)
Protein Binding
76%
Metabolized By
CYP3A4
External
Drugs.comStabilizes neuronal membranes by blocking voltage-sensitive sodium channels
Drug Class
Antiepileptic
Subclass
Sodium channel blocker
Half-life
25-65 hours initially, then 12-17 hours (auto-induction)
Time for plasma concentration to decrease by 50%
Protein Binding
76%
Fraction bound to plasma proteins
Therapeutic Index
Narrow
Margin between therapeutic and toxic doses