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Tylenol, Paracetamol, Panadol, Calpol, Little Fevers, Bactimicina, Pamprin Max Formula, Pamprin Multi-Symptom, Pamprin Cramp Formula, Percogesic Reformulated Jan 2011, Premsyn PMS, Panadol PM, CounterAct Pain, Capacet, Nortemp, Acetadryl, Ringl, Pharbetol, Arthriten Inflammatory Pain, Backaid, Cetafen, Exaprin, Backaid IPF, Lortab, Primlev, Verdrocet, Excedrin Mild Headache, Excedrin PM Triple Action, Ninjacof A, Vanatol, Fioricet, Sed-Max, Panadol Extra, Apadaz, Nalocet, Dvorah, Anacin AF, Bupap, Endocet, Esgic, Excedrin, Excedrin PM, Feverall, Fioricet with Codeine, Legatrin PM, Mapap, Marten-Tab, Norco, Redutemp, Repan, Saleto, Tempra Quicklets, Tencon, Tycolene, Tylenol Gelcap Extra Strength, Tylenol PM, Tylenol with Codeine, Unisom with Pain Relief, Vanquish, Zebutal, Acephen, Vtol, Allzital, Prolate, Combogesic, Exaprin Plus, Contragesic, Relagesic, Ultracet, Excedrin Tension Headache, Percocet, Lorcet, Frenadol, Dologesic, Hycet, Anabar, Ed Flex, By Ache, Excedrin Quick Tab, Comtrex Sore Throat Relief, Excedrin Back & Body, Anacin Advanced Headache Formula, Trezix, Tactinal, Backprin
Analgesic • Non-opioid analgesic / Antipyretic
PremiumInhibits central COX; exact mechanism not fully understood; acts centrally
From the drug index — may include conditions studied rather than approved indications
1 curated · 0 major or contraindicated · select a row for management
| Interacting drug | Severity | Effect |
|---|---|---|
| rifampicin | moderate | Increased risk of hepatotoxicity, especially at higher acetaminophen doses. Reduced analgesic/antipyretic effectiveness due to accelerated clearance. |
SEVERE hepatotoxicity risk. Maximum 2g/day with alcohol use. 3+ drinks/day + acetaminophen can be fatal.
Not recorded for Acetaminophen (Paracetamol). Absence here means this database does not hold a category — not that the drug is safe in pregnancy or breastfeeding.
Assembled from: drug index, curated drug database, curated interaction pairs.