Loading...
Vfend
Antifungal • Triazole antifungal
Half-life
6 hours (dose-dependent)
Protein Binding
58%
Metabolized By
CYP2C19, CYP2C9, CYP3A4
External
Drugs.comInhibits fungal CYP450-dependent 14-alpha-demethylase
Drug Class
Antifungal
Subclass
Triazole antifungal
Half-life
6 hours (dose-dependent)
Time for plasma concentration to decrease by 50%
Protein Binding
58%
Fraction bound to plasma proteins
Therapeutic Index
Narrow
Margin between therapeutic and toxic doses