Press Esc to close
Calan, Calan SR, Verelan, Isoptin
Calcium channel blocker • Non-dihydropyridine CCB
PremiumHalf-life
6-8 hours (single dose); 12 hours (chronic)
Protein Binding
90%
Metabolized By
CYP3A4, CYP1A2, CYP2C8
External
Drugs.comBlocks L-type calcium channels with prominent cardiac effects
From the drug index — may include conditions studied rather than approved indications
1 curated · 1 major or contraindicated · select a row for management
| Interacting drug | Severity | Effect |
|---|---|---|
| digoxin | major | 50-75% increase in digoxin levels plus bradycardia/AV block risk |
Additive hypotension; increases alcohol levels
Not recorded for Verapamil. Absence here means this database does not hold a category — not that the drug is safe in pregnancy or breastfeeding.
Assembled from: drug index, curated drug database, curated interaction pairs.