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Effexor XR
Antidepressant • SNRI
Half-life
5 hours (active metabolite 11 hours)
Protein Binding
27%
Metabolized By
CYP2D6, CYP3A4
External
Drugs.comInhibits serotonin and norepinephrine reuptake; weak dopamine reuptake inhibition
Drug Class
Antidepressant
Subclass
SNRI
Half-life
5 hours (active metabolite 11 hours)
Time for plasma concentration to decrease by 50%
Protein Binding
27%
Fraction bound to plasma proteins
Therapeutic Index
Wide
Margin between therapeutic and toxic doses