Fetal toxicity — discontinue when pregnancy detected
Clinical alerts
Boxed warning
1 boxed warning
Mechanism of action
Selectively blocks AT1 receptor, preventing angiotensin II effects
Recorded indications
From the drug index — may include conditions studied rather than approved indications
·Diabetic Nephropathies
·Heart Failure
·Takotsubo Cardiomyopathy
·Heart Dysfunction
·Heart Failure With Reduced Ejection Fraction
Interactions
No curated interaction pairs are recorded for Valsartan. This is not a statement that none exist — check a full interaction reference before combining.
Common adverse effects
Dizziness
Hyperkalemia
Fatigue
Food, alcohol & herbal
Food
Food decreases absorption by ~40%
Alcohol · moderate
Additive hypotension
Pharmacokinetics
Half-life
6 hours
Protein binding
95%
Metabolised by
CYP2C9
Pregnancy & lactation
Pregnancy category
D
Sources
Assembled from: drug index, curated drug database.
