Tamsulosin

Flomax

Alpha blocker • Alpha-1A selective antagonist

Half-life

9-13 hours

Protein Binding

94-99%

Metabolized By

CYP3A4, CYP2D6

External

Selectively blocks alpha-1A adrenergic receptors in the prostate and bladder neck

Drug Class

Alpha blocker

Subclass

Alpha-1A selective antagonist

Flomax

Half-life

9-13 hours

Time for plasma concentration to decrease by 50%

Protein Binding

94-99%

Fraction bound to plasma proteins

Therapeutic Index

Wide

Margin between therapeutic and toxic doses