Loading...
Belsomra
Hypnotic • Dual orexin receptor antagonist (DORA)
Blocks orexin-A and orexin-B from binding to OX1R and OX2R, promoting sleep
Drug Class
Hypnotic
Subclass
Dual orexin receptor antagonist (DORA)
Half-life
12 hours
Time for plasma concentration to decrease by 50%
Protein Binding
>99%
Fraction bound to plasma proteins
Therapeutic Index
Wide
Margin between therapeutic and toxic doses