Cyanide toxicity — must not be used at maximum dose for more than 10 minutes
Clinical alerts
Boxed warning
1 boxed warning
Narrow therapeutic index
Small dose changes can cause toxicity or loss of effect
Mechanism of action
Releases nitric oxide, causing both arterial and venous dilation
Interactions
No curated interaction pairs are recorded for Sodium Nitroprusside. This is not a statement that none exist — check a full interaction reference before combining.
Common adverse effects
Hypotension
Cyanide toxicity (prolonged use)
Nausea
Food, alcohol & herbal
Alcohol · major
Severe hypotension
Pharmacokinetics
Half-life
2 minutes
Protein binding
N/A
Pregnancy & lactation
Not recorded for Sodium Nitroprusside. Absence here means this database does not hold a category — not that the drug is safe in pregnancy or breastfeeding.
Sources
Assembled from: drug index, curated drug database.
