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  3. /Ropinirole

Ropinirole

Requip, Requip XL

Antiparkinson • Dopamine agonist (D2/D3 preferring)

Premium
CNS Depressant

Half-life

6 hours

Protein Binding

Metabolized By

CYP1A2

External

Drugs.com

Mechanism of Action

Directly stimulates D2/D3 dopamine receptors

Indications(5)

Idiopathic Parkinson's DiseaseParkinson's DiseaseParkinsonian DisordersAtypical Parkinson DiseaseProgressive Supranuclear Palsy

Classification

Drug Class

Antiparkinson

Subclass

Dopamine agonist (D2/D3 preferring)

Brand Names

RequipRequip XL

Key Properties

Half-life

6 hours

Time for plasma concentration to decrease by 50%

Protein Binding

—

Fraction bound to plasma proteins

Therapeutic Index

Wide

Margin between therapeutic and toxic doses

Not a substitute for clinical judgement
Ropinirole Drug Profile | PharmaGraphX