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Rizatriptan

Maxalt, Maxalt-MLT, Rizafilm, Symbravo

Antimigraine • Triptan (5-HT1B/1D agonist)

Premium

Serotoninergic

Half-life

2-3 hours

Protein Binding

14%

Metabolized By

MAO-A

External

Drugs.com

Clinical alerts

Serotonergic

Serotonin syndrome risk when combined with other serotonergic drugs

Mechanism of action

Agonist at 5-HT1B/1D receptors

Recorded indications

From the drug index — may include conditions studied rather than approved indications

·Migraine
·Brain Tumors
·Epilepsy
·Mild Cognitive Impairment
·Concussion

Interactions

No curated interaction pairs are recorded for Rizatriptan. This is not a statement that none exist — check a full interaction reference before combining.

Common adverse effects

Dizziness
Fatigue
Asthenia
Nausea

Food, alcohol & herbal

Food

ODT formulation dissolves on tongue; no water needed

Alcohol · minor

No significant interaction

Herbal

St. John's Wort (major) — Serotonin syndrome risk

Pharmacokinetics

Half-life: 2-3 hours
Protein binding: 14%
Metabolised by: MAO-A

Pregnancy & lactation

Not recorded for Rizatriptan. Absence here means this database does not hold a category — not that the drug is safe in pregnancy or breastfeeding.

Sources

Assembled from: drug index, curated drug database.

Not a substitute for clinical judgement