From the drug index — may include conditions studied rather than approved indications
·Hypertension, Pulmonary
·Chronic Thromboembolic Disease (CTED)
·Exercise Intolerance Post PEA Surgery
·Pulmonary Arterial Hypertension
·Eisenmenger Syndrome
Interactions
No curated interaction pairs are recorded for Riociguat. This is not a statement that none exist — check a full interaction reference before combining.
Common adverse effects
Headache
Dizziness
Dyspepsia
Nausea
Food, alcohol & herbal
Alcohol · moderate
Additive hypotension
Pharmacokinetics
Half-life
7-12 hours
Protein binding
95%
Metabolised by
CYP1A1, CYP3A4, CYP2C8
Pregnancy & lactation
Pregnancy category
X
Sources
Assembled from: drug index, curated drug database.
