Oxybutynin

Ditropan, Ditropan XL, Oxytrol

Urinary antispasmodic • Anticholinergic / Antimuscarinic

CNS Depressant

Half-life

2-3 hours (IR); 12-13 hours (ER)

Protein Binding

>99%

Metabolized By

CYP3A4

External

Antagonizes muscarinic receptors on bladder smooth muscle

Drug Class

Urinary antispasmodic

Subclass

Anticholinergic / Antimuscarinic

DitropanDitropan XLOxytrol

Half-life

2-3 hours (IR); 12-13 hours (ER)

Time for plasma concentration to decrease by 50%

Protein Binding

>99%

Fraction bound to plasma proteins

Therapeutic Index

Wide

Margin between therapeutic and toxic doses