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  3. /Oxybutynin

Oxybutynin

Ditropan, Ditropan XL, Oxytrol, Gelnique

Urinary antispasmodic • Anticholinergic / Antimuscarinic

Premium
CNS Depressant

Half-life

2-3 hours (IR); 12-13 hours (ER)

Protein Binding

Metabolized By

CYP3A4

External

Drugs.com

Mechanism of Action

Antagonizes muscarinic receptors on bladder smooth muscle

Indications(5)

Interstitial CystitisLevator SpasmBladder Pain SyndromeLocalized Prostate CancerPostoperative Urinary Incontinence

Classification

Drug Class

Urinary antispasmodic

Subclass

Anticholinergic / Antimuscarinic

Brand Names

DitropanDitropan XLOxytrolGelnique

Key Properties

Half-life

2-3 hours (IR); 12-13 hours (ER)

Time for plasma concentration to decrease by 50%

Protein Binding

—

Fraction bound to plasma proteins

Therapeutic Index

Wide

Margin between therapeutic and toxic doses

Not a substitute for clinical judgement
Oxybutynin Drug Profile | PharmaGraphX