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  3. /Morphine

Morphine

MS Contin, Kadian, Arymo, Duramorph, Infumorph, Mitigo

Opioid • Natural opioid agonist

Premium
NTICNS Depressant

Half-life

2-4 hours

Protein Binding

Metabolized By

UGT2B7

External

Drugs.com

Mechanism of Action

Agonist at mu-opioid receptors

Indications(5)

Relapsing Multiple SclerosisAlveolar RhabdomyosarcomaBotryoid-Type Embryonal RhabdomyosarcomaEmbryonal RhabdomyosarcomaRhabdomyosarcoma

Classification

Drug Class

Opioid

Subclass

Natural opioid agonist

Brand Names

MS ContinKadianArymoDuramorphInfumorphMitigo

Key Properties

Half-life

2-4 hours

Time for plasma concentration to decrease by 50%

Protein Binding

—

Fraction bound to plasma proteins

Therapeutic Index

Narrow

Margin between therapeutic and toxic doses

Not a substitute for clinical judgement
Morphine Drug Profile | PharmaGraphX