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  3. /Minocycline

Minocycline

Minocin, Solodyn, Dynacin, Ximino, Minolira, Amzeeq, Zilxi, Emrosi, Arestin, Cleeravue-M

Antibiotic • Tetracycline

Premium
Hepatotoxic

Half-life

11-22 hours

Protein Binding

Metabolized By

CYP3A4

External

Drugs.com

Mechanism of Action

Binds to 30S ribosomal subunit, inhibiting bacterial protein synthesis; better CNS penetration

Indications(5)

Treatment Resistant DepressionHelicobacter Pylori InfectionStrokeIschemia StrokeHemorrhagic Strokes

Classification

Drug Class

Antibiotic

Subclass

Tetracycline

Brand Names

MinocinSolodynDynacinXiminoMinoliraAmzeeqZilxiEmrosiArestinCleeravue-M

Key Properties

Half-life

11-22 hours

Time for plasma concentration to decrease by 50%

Protein Binding

—

Fraction bound to plasma proteins

Therapeutic Index

Wide

Margin between therapeutic and toxic doses

Not a substitute for clinical judgement
Minocycline Drug Profile | PharmaGraphX