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  3. /Methimazole

Methimazole

Tapazole, Felanorm, Felimazole

Antithyroid • Thioamide

Premium
Hepatotoxic

Half-life

5-6 hours

Protein Binding

Metabolized By

N/A

External

Drugs.com

Mechanism of Action

Inhibits thyroid peroxidase, blocking thyroid hormone synthesis

Indications(5)

GlioblastomaGliomaGraves DiseaseGraves' DiseaseHyperthyroidism

Classification

Drug Class

Antithyroid

Subclass

Thioamide

Brand Names

TapazoleFelanormFelimazole

Key Properties

Half-life

5-6 hours

Time for plasma concentration to decrease by 50%

Protein Binding

—

Fraction bound to plasma proteins

Therapeutic Index

Wide

Margin between therapeutic and toxic doses

Not a substitute for clinical judgement
Methimazole Drug Profile | PharmaGraphX