Meropenem

Binds PBP2 and PBP3; broad-spectrum cell wall synthesis inhibition

• ·Infection
• ·Sepsis
• ·NICU
• ·PICU
• ·Beta Lactams

Therapeutic range

2–16 mg/L

fT>MIC ≥ 40-100%

No curated interaction pairs are recorded for Meropenem. This is not a statement that none exist — check a full interaction reference before combining.

• Diarrhea
• Nausea
• Headache
• Rash

Half-life

1 hour

Protein binding

2%

Clearance

14 L/h

critically ill adult patients

Volume of distribution

20 L

Renally eliminated

70%

Dose review in renal impairment

Model

2-compartment

Not recorded for Meropenem. Absence here means this database does not hold a category — not that the drug is safe in pregnancy or breastfeeding.