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  3. /Mebendazole

Mebendazole

Vermox, Emverm

Antiparasitic • Benzimidazole anthelmintic

Premium
Hepatotoxic

Half-life

2.5-5.5 hours

Protein Binding

Metabolized By

CYP1A2, CYP2C9

External

Drugs.com

Mechanism of Action

Inhibits microtubule synthesis in helminths, blocking glucose uptake

Classification

Drug Class

Antiparasitic

Subclass

Benzimidazole anthelmintic

Brand Names

VermoxEmverm

Key Properties

Half-life

2.5-5.5 hours

Time for plasma concentration to decrease by 50%

Protein Binding

—

Fraction bound to plasma proteins

Therapeutic Index

Wide

Margin between therapeutic and toxic doses

Not a substitute for clinical judgement
Mebendazole Drug Profile | PharmaGraphX