Mebendazole

Vermox, Emverm

Antiparasitic • Benzimidazole anthelmintic

Hepatotoxic

Half-life

2.5-5.5 hours

Protein Binding

95%

Metabolized By

CYP1A2, CYP2C9

External

Inhibits microtubule synthesis in helminths, blocking glucose uptake

Drug Class

Antiparasitic

Subclass

Benzimidazole anthelmintic

VermoxEmverm

Half-life

2.5-5.5 hours

Time for plasma concentration to decrease by 50%

Protein Binding

95%

Fraction bound to plasma proteins

Therapeutic Index

Wide

Margin between therapeutic and toxic doses