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  3. /Levofloxacin

Levofloxacin

Levaquin

Antibiotic • Fluoroquinolone

Premium
QT RiskNephrotoxic

Half-life

6-8 hours

Protein Binding

Metabolized By

N/A

External

Drugs.com

Mechanism of Action

Inhibits bacterial DNA gyrase and topoisomerase IV

Indications(5)

Tuberculosis, LatentH Pylori InfectionHELICOBACTER PYLORI INFECTIONSGranulomatous MastitisPeriprosthetic Joint Infection (PJI)

Classification

Drug Class

Antibiotic

Subclass

Fluoroquinolone

Brand Names

Levaquin

Key Properties

Half-life

6-8 hours

Time for plasma concentration to decrease by 50%

Protein Binding

—

Fraction bound to plasma proteins

Therapeutic Index

Wide

Margin between therapeutic and toxic doses

Not a substitute for clinical judgement
Levofloxacin Drug Profile | PharmaGraphX