Levetiracetam

Binds to synaptic vesicle protein SV2A, modulating neurotransmitter release

Therapeutic range

12–46 mg/L

No curated interaction pairs are recorded for Levetiracetam. This is not a statement that none exist — check a full interaction reference before combining.

• Somnolence
• Dizziness
• Behavioral changes
• Irritability
• Weakness

Half-life

6-8 hours

Protein binding

<10%

Clearance

4 L/h

adult epilepsy patients

Volume of distribution

40 L

Bioavailability

100%

Renally eliminated

66%

Dose review in renal impairment

Model

1-compartment

Not recorded for Levetiracetam. Absence here means this database does not hold a category — not that the drug is safe in pregnancy or breastfeeding.