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Harvoni
Antiviral • NS5A inhibitor + NS5B inhibitor (HCV)
Half-life
47 hours (ledipasvir); 27 hours (sofosbuvir metabolite)
Protein Binding
99.8% (ledipasvir)
Metabolized By
N/A
External
Drugs.comLedipasvir inhibits NS5A; sofosbuvir inhibits NS5B polymerase
No curated interaction pairs are recorded for Ledipasvir/Sofosbuvir. This is not a statement that none exist — check a full interaction reference before combining.
No significant interaction
Not recorded for Ledipasvir/Sofosbuvir. Absence here means this database does not hold a category — not that the drug is safe in pregnancy or breastfeeding.
Assembled from: drug index, curated drug database.