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  3. /Hydralazine

Hydralazine

Apresoline

Vasodilator • Direct arterial vasodilator

Premium
Hepatotoxic

Half-life

3-7 hours

Protein Binding

Metabolized By

NAT2 (acetylation)

External

Drugs.com

Mechanism of Action

Directly relaxes arterial smooth muscle; exact mechanism unknown

Classification

Drug Class

Vasodilator

Subclass

Direct arterial vasodilator

Brand Names

Apresoline

Key Properties

Half-life

3-7 hours

Time for plasma concentration to decrease by 50%

Protein Binding

—

Fraction bound to plasma proteins

Therapeutic Index

Wide

Margin between therapeutic and toxic doses

Not a substitute for clinical judgement
Hydralazine Drug Profile | PharmaGraphX