Glucagon

Agonist at hepatic glucagon receptors, raising cyclic AMP to drive glycogenolysis and gluconeogenesis and so blood glucose. Also used in beta-blocker and calcium-channel-blocker overdose, where its inotropic effect bypasses adrenergic receptor blockade. A peptide, cleared by proteolysis rather than cytochrome P450.

No curated interaction pairs are recorded for Glucagon. This is not a statement that none exist — check a full interaction reference before combining.

• Nausea
• Vomiting
• Headache
• Transient hypertension

Half-life

8-18 minutes

Protein binding

Negligible

Not recorded for Glucagon. Absence here means this database does not hold a category — not that the drug is safe in pregnancy or breastfeeding.