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Glimepiride

Amaryl, Duetact

Uncategorized

Standard

Half-life

5-8 hours

Protein Binding

99.5%

Metabolized By

N/A

External

Drugs.com

Mechanism of action

Stimulates insulin secretion from pancreatic beta cells via SUR1 receptor

Recorded indications

From the drug index — may include conditions studied rather than approved indications

·Type 2 Diabetes
·Comparative Effectiveness of Glycemia-lowering Medications
·Diabete Type 2
·Type 2 Diabetes Mellitus
·Type 2 Diabetes Mellitus (T2DM)

Interactions

No curated interaction pairs are recorded for Glimepiride. This is not a statement that none exist — check a full interaction reference before combining.

Common adverse effects

Hypoglycemia
Weight gain
Dizziness

Food, alcohol & herbal

Food

Take with first main meal

Alcohol · major

Severe hypoglycemia risk

Pharmacokinetics

Half-life: 5-8 hours
Protein binding: 99.5%
Metabolised by: CYP2C9

Pregnancy & lactation

Not recorded for Glimepiride. Absence here means this database does not hold a category — not that the drug is safe in pregnancy or breastfeeding.

Sources

Assembled from: drug index, curated drug database.

Not a substitute for clinical judgement