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Neurontin, Gralise, Horizant, Gabarone
Anticonvulsant • GABA analog / Calcium channel modulator
PremiumHalf-life
5-7 hours
Protein Binding
<3%
Metabolized By
CYP1A2, CYP2A6, CYP2C9, CYP2C19, CYP2D6, CYP2E1, CYP3A4
External
Drugs.comBinds to alpha-2-delta subunit of voltage-gated calcium channels, reducing excitatory neurotransmitter release
No curated interaction pairs are recorded for Gabapentin. This is not a statement that none exist — check a full interaction reference before combining.
Additive CNS depression
Not recorded for Gabapentin. Absence here means this database does not hold a category — not that the drug is safe in pregnancy or breastfeeding.
Assembled from: drug index, curated drug database.