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  3. /Furosemide

Furosemide

Lasix, Disal, Furoscix, Salix - substance

Diuretic • Loop diuretic

Premium
Nephrotoxic

Half-life

2 hours

Protein Binding

Metabolized By

N/A

External

Drugs.com

Mechanism of Action

Inhibits sodium-potassium-chloride cotransporter in thick ascending limb of Henle

Indications(5)

Heart FailureFluid OverloadAdvanced Solid MalignanciesHealthySalt-Sensitivity of Blood Pressure

Classification

Drug Class

Diuretic

Subclass

Loop diuretic

Brand Names

LasixDisalFuroscixSalix - substance

Key Properties

Half-life

2 hours

Time for plasma concentration to decrease by 50%

Protein Binding

—

Fraction bound to plasma proteins

Therapeutic Index

Wide

Margin between therapeutic and toxic doses

Not a substitute for clinical judgement
Furosemide Drug Profile | PharmaGraphX