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Lasix
Diuretic • Loop diuretic
Inhibits sodium-potassium-chloride cotransporter in thick ascending limb of Henle
Drug Class
Diuretic
Subclass
Loop diuretic
Half-life
2 hours
Time for plasma concentration to decrease by 50%
Protein Binding
91-99%
Fraction bound to plasma proteins
Therapeutic Index
Wide
Margin between therapeutic and toxic doses