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  3. /Fluticasone

Fluticasone

Flovent, Flonase, Arnuity, Cutivate, Dymista, Breo, Clarispray, Aller-Flo, Flonase Sensimist, Nasopro 24, AirDuo, Armonair, Trelegy, Xhance, Fluticare, Wixela, Beser, Advair

Corticosteroid • Inhaled corticosteroid (ICS)

Premium

Half-life

7.8 hours (inhaled)

Protein Binding

Metabolized By

CYP3A4

External

Drugs.com

Mechanism of Action

Binds to glucocorticoid receptors, suppressing inflammatory gene transcription

Indications(5)

AsthmaChronic Rhinosinusitis Without Nasal PolypsEosinophilic EsophagitisEustachian Tube DysfunctionHealthy

Classification

Drug Class

Corticosteroid

Subclass

Inhaled corticosteroid (ICS)

Brand Names

FloventFlonaseArnuityCutivateDymistaBreoClarisprayAller-FloFlonase SensimistNasopro 24AirDuoArmonairTrelegyXhanceFluticareWixelaBeserAdvair

Key Properties

Half-life

7.8 hours (inhaled)

Time for plasma concentration to decrease by 50%

Protein Binding

—

Fraction bound to plasma proteins

Therapeutic Index

Wide

Margin between therapeutic and toxic doses

Not a substitute for clinical judgement
Fluticasone Drug Profile | PharmaGraphX