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Finasteride

Propecia, Proscar, Entadfi

Androgen inhibitor • 5-alpha reductase inhibitor

Premium

Half-life

5-6 hours (elderly: 8 hours)

Protein Binding

Metabolized By

CYP3A4

External

Drugs.com

Mechanism of Action

Inhibits type II 5-alpha reductase, reducing DHT production

Indications(5)

BPH (Benign Prostatic Hyperplasia)Lower Urinary Track SymptomsAndrogenic AlopeciaMale Pattern of Hair Loss, Androgenic AlopeciaAndrogenetic Alopecia (AGA)

Classification

Drug Class

Androgen inhibitor

Subclass

5-alpha reductase inhibitor

Brand Names

PropeciaProscarEntadfi

Key Properties

Half-life

5-6 hours (elderly: 8 hours)

Time for plasma concentration to decrease by 50%

Protein Binding

—

Fraction bound to plasma proteins

Therapeutic Index

Wide

Margin between therapeutic and toxic doses

Not a substitute for clinical judgement
Finasteride Drug Profile | PharmaGraphX