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Allegra
Antihistamine • Second-generation H1 antihistamine
Active metabolite of terfenadine; H1 antagonist with no CNS penetration
Drug Class
Antihistamine
Subclass
Second-generation H1 antihistamine
Half-life
14.4 hours
Time for plasma concentration to decrease by 50%
Protein Binding
60-70%
Fraction bound to plasma proteins
Therapeutic Index
Wide
Margin between therapeutic and toxic doses