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Ezetimibe

Nexlizet, Roszet, Zetia, Vytorin

Uncategorized

Standard

Half-life

22 hours

Protein Binding

99.7%

Metabolized By

N/A

External

Drugs.com

Mechanism of action

Inhibits NPC1L1 protein at intestinal brush border, reducing cholesterol absorption

Recorded indications

From the drug index — may include conditions studied rather than approved indications

·Acute Coronary Syndromes (ACS)
·Primary Hypercholesterolaemia
·Mixed Dyslipidemia
·Hypercholesterolemia
·Pancreatic Ductal Adenocarcinoma

Interactions

No curated interaction pairs are recorded for Ezetimibe. This is not a statement that none exist — check a full interaction reference before combining.

Common adverse effects

Diarrhea
Arthralgia
Upper respiratory infection

Pharmacokinetics

Half-life: 22 hours
Protein binding: 99.7%

Pregnancy & lactation

Not recorded for Ezetimibe. Absence here means this database does not hold a category — not that the drug is safe in pregnancy or breastfeeding.

Sources

Assembled from: drug index, curated drug database.

Not a substitute for clinical judgement