Etanercept

Enbrel, Erelzi

Biologic • TNF-alpha inhibitor

Half-life

102 hours

Protein Binding

N/A

Metabolized By

Proteolytic degradation

External

Fusion protein (TNF receptor + IgG1 Fc) that binds and inactivates TNF-alpha

Drug Class

Biologic

Subclass

TNF-alpha inhibitor

EnbrelErelzi

Half-life

102 hours

Time for plasma concentration to decrease by 50%

Protein Binding

N/A

Fraction bound to plasma proteins

Therapeutic Index

Wide

Margin between therapeutic and toxic doses