Dexamethasone

Decadron, Tresaderm, Dexium, Maxitrol, Dexasone, Maxidex, Dexycu, Dextenza, Poly-Dex, Tobradex, Hemady, Ciprodex, Ozurdex

Corticosteroid • Glucocorticoid

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Half-life

36-54 hours

Protein Binding

68%

Metabolized By

CYP3A4

External

Drugs.com

Mechanism of action

Potent glucocorticoid with minimal mineralocorticoid activity

Recorded indications

From the drug index — may include conditions studied rather than approved indications

·Multiple Myeloma, Newly Diagnosed
·Multiple Myeloma
·Gastroesophageal Junction
·Gastroesophageal Adenocarcinoma
·Esophageal Neoplasms

Interactions

No curated interaction pairs are recorded for Dexamethasone. This is not a statement that none exist — check a full interaction reference before combining.

Common adverse effects

Insomnia
Mood changes
Hyperglycemia
Weight gain
Immunosuppression

Food, alcohol & herbal

Food

Take with food

Alcohol · moderate

Increased GI irritation

Pharmacokinetics

Half-life: 36-54 hours
Protein binding: 68%
Metabolised by: CYP3A4
Induces: CYP3A4, CYP2C9, CYP2B6

Pregnancy & lactation

Not recorded for Dexamethasone. Absence here means this database does not hold a category — not that the drug is safe in pregnancy or breastfeeding.

Sources

Assembled from: drug index, curated drug database.

Not a substitute for clinical judgement