PharmaGraphX

Log in Get Started

Desvenlafaxine

Khedezla, Pristiq

Uncategorized

Standard

Half-life

11 hours

Protein Binding

30%

Metabolized By

N/A

External

Drugs.com

Boxed warning

Suicidality in children, adolescents, and young adults

Clinical alerts

Boxed warning

1 boxed warning

Bleeding risk

Additive with other antithrombotics and NSAIDs

Serotonergic

Serotonin syndrome risk when combined with other serotonergic drugs

Mechanism of action

Inhibits reuptake of serotonin and norepinephrine

Recorded indications

From the drug index — may include conditions studied rather than approved indications

·Hot Flashes
·Migraine
·Herpes Zoster
·Pain
·Tension Type Headache

Interactions

No curated interaction pairs are recorded for Desvenlafaxine. This is not a statement that none exist — check a full interaction reference before combining.

Common adverse effects

Nausea
Dizziness
Insomnia
Hyperhidrosis

Food, alcohol & herbal

Alcohol · major

Additive CNS depression

Herbal

St. John's Wort (major) — Serotonin syndrome risk

Pharmacokinetics

Half-life: 11 hours
Protein binding: 30%
Metabolised by: CYP3A4

Pregnancy & lactation

Not recorded for Desvenlafaxine. Absence here means this database does not hold a category — not that the drug is safe in pregnancy or breastfeeding.

Sources

Assembled from: drug index, curated drug database.

Not a substitute for clinical judgement

Desvenlafaxine

Khedezla, Pristiq

Uncategorized

Standard

Half-life

11 hours

Protein Binding

30%

Metabolized By

N/A

External

Drugs.com

Boxed warning

Suicidality in children, adolescents, and young adults

Clinical alerts

Boxed warning

1 boxed warning

Bleeding risk

Additive with other antithrombotics and NSAIDs

Serotonergic

Serotonin syndrome risk when combined with other serotonergic drugs

Mechanism of action

Inhibits reuptake of serotonin and norepinephrine

Recorded indications

From the drug index — may include conditions studied rather than approved indications

·Hot Flashes
·Migraine
·Herpes Zoster
·Pain
·Tension Type Headache

Interactions

No curated interaction pairs are recorded for Desvenlafaxine. This is not a statement that none exist — check a full interaction reference before combining.

Common adverse effects

Nausea
Dizziness
Insomnia
Hyperhidrosis

Food, alcohol & herbal

Alcohol · major

Additive CNS depression

Herbal

St. John's Wort (major) — Serotonin syndrome risk

Pharmacokinetics

Half-life: 11 hours
Protein binding: 30%
Metabolised by: CYP3A4

Pregnancy & lactation

Not recorded for Desvenlafaxine. Absence here means this database does not hold a category — not that the drug is safe in pregnancy or breastfeeding.

Sources

Assembled from: drug index, curated drug database.

Not a substitute for clinical judgement