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  3. /Cetirizine

Cetirizine

Zyrtec, Wal-Zyr, Wal Zyr 24 Hour Allergy, Zerviate, Quzyttir, Zyrtec-D, Aller-Tec, Aller-Tec D, Alleroff, Wal Zyr D

Antihistamine • Second-generation H1 antihistamine

Premium
CNS Depressant

Half-life

8.3 hours

Protein Binding

Metabolized By

CYP3A4

External

Drugs.com

Mechanism of Action

Selective peripheral H1 receptor antagonist with minimal CNS penetration

Indications(5)

Breast CancerMultiple SclerosisNon-Small Cell Lung CancerMetastatic Non-small Cell Lung CancerLiver Metastases

Classification

Drug Class

Antihistamine

Subclass

Second-generation H1 antihistamine

Brand Names

ZyrtecWal-ZyrWal Zyr 24 Hour AllergyZerviateQuzyttirZyrtec-DAller-TecAller-Tec DAlleroffWal Zyr D

Key Properties

Half-life

8.3 hours

Time for plasma concentration to decrease by 50%

Protein Binding

—

Fraction bound to plasma proteins

Therapeutic Index

Wide

Margin between therapeutic and toxic doses

Not a substitute for clinical judgement
Cetirizine Drug Profile | PharmaGraphX