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Cetirizine

Zyrtec, Wal-Zyr, Wal Zyr 24 Hour Allergy, Zerviate, Quzyttir, Zyrtec-D, Aller-Tec, Aller-Tec D, Alleroff, Wal Zyr D

Antihistamine • Second-generation H1 antihistamine

Premium

CNS Depressant

Half-life

8.3 hours

Protein Binding

93%

Metabolized By

CYP3A4

External

Drugs.com

Clinical alerts

CNS depressant

Additive sedation with other CNS depressants and alcohol

Mechanism of action

Selective peripheral H1 receptor antagonist with minimal CNS penetration

Recorded indications

From the drug index — may include conditions studied rather than approved indications

·Breast Cancer
·Multiple Sclerosis
·Non-Small Cell Lung Cancer
·Metastatic Non-small Cell Lung Cancer
·Liver Metastases

Interactions

No curated interaction pairs are recorded for Cetirizine. This is not a statement that none exist — check a full interaction reference before combining.

Common adverse effects

Drowsiness
Dry mouth
Fatigue
Headache

Food, alcohol & herbal

Alcohol · moderate

Additive sedation

Pharmacokinetics

Half-life: 8.3 hours
Protein binding: 93%
Metabolised by: CYP3A4

Pregnancy & lactation

Not recorded for Cetirizine. Absence here means this database does not hold a category — not that the drug is safe in pregnancy or breastfeeding.

Sources

Assembled from: drug index, curated drug database.

Not a substitute for clinical judgement