Ceftazidime/Avibactam

Avycaz

Antibiotic • Cephalosporin + beta-lactamase inhibitor

Half-life

2.7 hours (ceftazidime); 2.7 hours (avibactam)

Protein Binding

<10%

Metabolized By

N/A

External

Drugs.com

Mechanism of action

Ceftazidime inhibits PBPs; avibactam inhibits class A, C, and some D beta-lactamases

Interactions

No curated interaction pairs are recorded for Ceftazidime/Avibactam. This is not a statement that none exist — check a full interaction reference before combining.

Common adverse effects

Nausea
Vomiting
Diarrhea
Positive Coombs test

Food, alcohol & herbal

Alcohol · minor

No significant interaction

Pharmacokinetics

Half-life: 2.7 hours (ceftazidime); 2.7 hours (avibactam)
Protein binding: <10%

Pregnancy & lactation

Not recorded for Ceftazidime/Avibactam. Absence here means this database does not hold a category — not that the drug is safe in pregnancy or breastfeeding.

Sources

Assembled from: drug index, curated drug database.

Not a substitute for clinical judgement