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Principen, Omnipen
Antibiotic • Aminopenicillin
Inhibits bacterial cell wall synthesis by binding to PBPs
Drug Class
Antibiotic
Subclass
Aminopenicillin
Half-life
1-2 hours
Time for plasma concentration to decrease by 50%
Protein Binding
20%
Fraction bound to plasma proteins
Therapeutic Index
Wide
Margin between therapeutic and toxic doses